Tuna, IgE, Serum
Use
The Tuna, IgE, Serum test is useful for establishing a diagnosis of an allergy to tuna and defining the allergen responsible for eliciting signs and symptoms. It helps identify allergens responsible for an allergic response and/or anaphylactic episodes. The test is also used to confirm sensitization prior to beginning immunotherapy and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Special Instructions
For a listing of allergens available for testing, see the linked Allergens - Immunoglobulin E (IgE) Antibodies PDF. If not ordering electronically, complete and send an Allergen Test Request form (T236) with the specimen.
Limitations
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists. Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies, which must be interpreted in the clinical context. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6270-3
- 6270-3
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL, For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel, Acceptable: Red top, Submission Container/Tube: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
