Vitamin A and Vitamin E, Serum
Use
This test is used for assessing the status and monitoring the therapy of vitamin A and E. Vitamin A plays a crucial role in vision, immune function, and cellular communication. Vitamin E acts as an antioxidant, protecting cells from damage. Deficiencies in these vitamins can lead to clinical conditions, and excess can be toxic. Evaluating individuals with intestinal lipid malabsorption is another application of this test.
Special Instructions
The test includes Vitamin A and Vitamin E assessments, both performed using liquid chromatography-tandem mass spectrometry. Ensure proper patient preparation regarding fasting and abstinence from alcohol before specimen collection.
Limitations
Nonfasting specimens or those affected by recent vitamin supplementation may yield elevated serum vitamin concentrations, leading to potential misinterpretation of test results. Acute alcohol ingestion can falsely increase serum vitamin A levels. Patients should adhere to preparatory instructions to avoid these confounders.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 96600-2
- 1823-4
- 2923-1
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL serum
Minimum Volume
0.5 mL
Container
Amber vial
Collection Instructions
Within 2 hours of collection, centrifuge and aliquot serum into a light protected plastic vial.
Patient Preparation
1. Fasting: 12 hours, required; infants should have specimen collected before next feeding. 2. Patient must not consume any alcohol for 24 hours before specimen collection.
Storage Instructions
Ship specimen in amber vial to protect from light.
Causes for Rejection
Gross lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 28 days |
| Frozen | 28 days |