Anaplastic Lymphoma Kinase-1, technical only
Use
Anaplastic lymphoma kinase (ALK) receptor aberrant protein expression, gene mutations, and fusions is observed in various cancer types including anaplastic large cell lymphoma. ALK protein detection by immunohistochemistry is used for tumor classification and may also be indicative of an underlying ALK gene mutation or translocation.
Special Instructions
Not provided.
Limitations
Technical component only. Pathologist read not included.
Methodology
Immunoassay (IHC)
Biomarkers
Anaplastic lymphoma kinase -1
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.