c-MYC, technical only
Use
c-MYC is a proto-oncogene that produces a short-lived nuclear phosphoprotein. Its overexpression is implicated in various hematopoietic tumors. Dual overexpression with BCL2 is associated with poor outcomes in diffuse large B cell lymphoma (DLBCL).
Special Instructions
This is a technical component only test. Pathologist read is not included.
Limitations
This test does not include a pathologist read, which may limit interpretive insights. Clinical correlation is necessary for a comprehensive assessment. Test results may be affected by tissue preservation quality and fixation conditions.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED). Formalin-fixed Paraffin Embedded Tissue (FFPE Block, Formalin Fixed); Unstained slides: 2 slides (3-5 μM) per stain (min 1 slide per stain), Formalin Fixed.
Storage Instructions
Store slides and blocks at 15°C to 25°C.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |