Chromosome Analysis Lymph Node (Lymphoma)
Use
This test performs chromosome analysis on lymph node samples, providing valuable information in the context of lymphoma diagnosis and management. The analysis involves karyotyping, which is essential in identifying chromosomal abnormalities associated with various types of lymphomas.
Special Instructions
All attempts will be made to process and report samples received more than 72 hours post-collection. Note that bone marrow is the preferred sample type for most hematological malignancies, which should be considered when ordering this test.
Limitations
The sample's stability is crucial, with a maximum stability period of 72 hours. Processing delays can occur if specimens are received outside this stability window. Samples that are clotted, exposed to extreme temperatures, contain anticoagulants toxic to cells, or have an insufficient number of cells will be rejected, impacting the test's effectiveness and accuracy.
Methodology
Chromosomal / Cytogenetics (Karyotype)
Biomarkers
Result Turnaround Time
7 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
10 mm
Minimum Volume
Not provided
Container
10 mL sterile transport tube
Collection Instructions
Place sample in at least 4 mL tissue culture transport media (RPMI). Ensure use of a refrigerated gel pack in the shipment to prevent exposure to high temperatures.
Storage Instructions
Store lymph node samples at 2°C to 25°C. For fixed cytogenetically prepared cells, store at -28°C to -15°C.
Causes for Rejection
Clotted specimen; Exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 Hours |