DEK::NUP214; t(6;9) FISH Test
Use
This FISH test is used to detect the DEK::NUP214 gene fusion associated with the chromosomal translocation t(6;9), which is observed in myeloid malignancies, particularly in acute myeloid leukemia. It aids in the diagnosis and management of patients with these conditions.
Special Instructions
All attempts will be made to process and report samples received more than 72 hours post-collection. Bone marrow is the sample of choice in most hematologic malignancies.
Limitations
The success of the FISH analysis depends on specimen quality and the presence of sufficient numbers of target cells. Specimens that do not meet the minimum requirements may result in test rejection or suboptimal performance.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
Not provided
Container
EDTA preferred (NaHep accepted)
Storage Instructions
2°C to 25°C
Causes for Rejection
Clotted specimen; Specimen exposed to extreme temperatures; Anticoagulant toxic to cells; Insufficient number of cells
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |