Grocott's Methenamine Silver Stain, technical only
Use
Grocott methenamine silver (GMS) stain is used to detect fungi, including Pneumocystis jirovecii, the causative agent of Pneumocystis pneumonia. This stain imparts a black color to fungal cell walls, facilitating their identification under a microscope. Additionally, GMS can stain other organisms and non-organic substances, such as melanin, mucins, and glycogen, providing valuable diagnostic information.
Special Instructions
Technical component only. Pathologist read not included.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Other
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
FFPE Block, Formalin Fixed
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Storage Instructions
Specimens may be transferred to 70% alcohol for transportation purposes after fixation.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |