HSV Type I and II, technical only
Use
Herpes simplex virus (HSV) type I and II antibody detects both types of HSV without cross-reactivity with CMV or Epstein-Barr virus. HSV infection may be observed in genitalia mucosal surfaces, skin, or internal organs of immunocompromised individuals.
Special Instructions
Technical component only. Pathologist read not included. Fresh Tissues: Specimens may be fixed in formalin for 24-72 hours by collection sites, then transferred to 70% ethanol and stored at 2-8°C for longer term storage if needed. Samples must be tested 3 months after placing in ethanol. Unstained slides: Positively charged glass slides required to prevent background staining and prevent tissue loss. Slides should be left unbaked.
Limitations
Only detects HSV type I and II; does not detect CMV or Epstein-Barr virus. Specimens not fixed in 10% NBF or B plus will be rejected. Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
8 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED)
Storage Instructions
Specimens may be transferred to 70% alcohol for transportation purposes after fixation in 10% NBF or B plus.
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |
| Refrigerated | N/A |
| Frozen | N/A |