Human glial fibrillary acidic protein (GFAP)
Use
GFAP (Glial Fibrillary Acidic Protein) is an intermediate filament protein predominantly expressed in astrocytes and other glial cells in the central nervous system. In pathology, GFAP is used to identify astrocytic tumors and to distinguish them from other types of central nervous system neoplasms. Its expression also aids in the diagnosis of conditions like reactive gliosis and Alexander disease, where abnormal GFAP accumulation is observed.
Special Instructions
Not provided.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract. Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
GFAP
Protein
Result Turnaround Time
8 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fresh)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED)
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |