IGH::MALT1; t(14;18)
Use
FISH test on hematologic specimens for detection of IGH::MALT1 gene fusion. This fusion, associated with t(14;18), may be observed in marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT lymphoma) cases.
Special Instructions
All attempts will be made to process and report samples received > 72 hours post-collection. Bone marrow is the sample of choice in most heme malignancies.
Limitations
The test is designed for clinical detection of IGH::MALT1 fusions in hematologic malignancies. Samples exposed to temperatures outside recommended range, clotted specimens, and those with insufficient cells are subject to rejection.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
Not provided
Container
EDTA preferred (NaHep accepted)
Storage Instructions
2°C to 25°C
Causes for Rejection
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |