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PDGFRB 5q32 Rearrangement — MPLN | Casandra.ai

Casandra

Casandra Test Code MP78504Version 1 (DRAFT)

Performing Lab

Lab MPLNLab Test ID F PDGFRBCPT Codes 88374, 88377

PDGFRB 5q32 Rearrangement

Clinical Use

Use

This FISH test is used for the detection of PDGFRB (5q32) gene rearrangement in hematologic specimens. The rearrangement of PDGFRB is often associated with chronic myeloproliferative disorders (CMPD), myelodysplastic/myeloproliferative syndromes (MDS/MPD), and acute myeloid leukemia (AML), frequently linked to symptoms like eosinophilia and splenomegaly. It is commonly ordered as part of the F EOSINOPHILA Panel.

Special Instructions

Not provided.

Limitations

Turnaround times are primarily for clinical use and may vary according to specific biopharma protocol requirements. Final turnaround times will be confirmed in the biopharma study contract.

Test Details

Methodology

Chromosomal / Cytogenetics (FISH)

Biomarkers

Chromosome 5q32

Chromosome

Copy Number Alteration

Copy Number Alteration • Categorical (e.g., Positive / Negative / Indeterminate)

Result Turnaround Time

5 days

Related Documents

For more information, please review the documents below

Lab test overview

Specimen Requirements

Specimen

Whole Blood

Volume

5 mL

Minimum Volume

Not provided

Container

EDTA preferred (NaHep accepted)

Storage Instructions

2°C to 25°C

Causes for Rejection

Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells

Stability Requirements

Temperature	Period
Room Temperature	72 hours