SOX10, technical only
Use
SOX10 is a transcription factor that plays a crucial role in the development of neural crest cells and is widely used in pathology to identify neural crest-derived tumors. It is particularly valuable in diagnosing melanoma, schwannomas, and peripheral nerve sheath tumors, where its expression helps distinguish these from other neoplasms.
Special Instructions
Technical component only. Pathologist read not included. Fresh Tissues: Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin for 6-72 hours. Unstained slides: Positively charged glass slides required to prevent background staining and tissue loss.
Limitations
Specimens must be tested 3 months after placing in ethanol. Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
FFPE Block, Formalin Fixed
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |