Thyroglobulin
Use
Thyroglobulin is a glycoprotein produced and stored by thyroid follicular cells. It is used in pathology to identify thyroid-originating tumors. Its expression helps differentiate thyroid neoplasms from other types of malignancies, thus being essential in the diagnosis and management of conditions related to thyroid cancer.
Special Instructions
Fresh Tissues must be fixed in formalin for 24-72 hours at collection sites, and can then be transferred to 70% ethanol for longer storage if required. Unstained slides should be left unbaked and positively charged glass slides are necessary to prevent background staining and tissue loss.
Limitations
Specimens must be fixed in 10% neutral buffered formalin or B plus. Use of any other fixatives will lead to specimen rejection. The turnaround time and conditions for sample handling are strictly for clinical use and may change depending on specific biopharma protocol requirements.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
8 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Formalin Fixed
Collection Instructions
Use a fixative to tissue ratio of 20:1, 10% neutral buffered formalin for 6-72 hours. After fixation, tissues can be transferred to 70% ethanol.
Storage Instructions
Store at 15°C to 25°C. Use a refrigerated gel pack during shipment to avoid extreme temperatures.
Causes for Rejection
Any fixative other than 10% neutral buffered formalin or B plus will result in rejection.