ALK for NSCLC
Also known as: Anaplastic lymphoma kinase
Use
The ALK for NSCLC FISH test is designed to detect rearrangements in the ALK gene which can be indicative of non-small cell lung carcinoma (NSCLC). This test helps in identifying patients who may benefit from targeted therapies against ALK rearrangements, a feature in a subset of NSCLC.
Special Instructions
For tech-only services, circle H&E on the slide for identification. Use cold packs during transport, ensuring they do not contact specimens directly.
Limitations
The FISH test detects ALK rearrangements but cannot determine the biological significance of such rearrangements. Certain factors such as improper specimen handling can affect results. The test is specific to non-small cell lung carcinoma and may not be applicable to other cancers.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Paraffin Block: H&E slide plus paraffin block or 2 unstained slides cut at 4 microns
Collection Instructions
Paraffin Block: H&E slide (required) plus paraffin block. Cut Slides: H&E slide (required) plus 2 unstained slides cut at 4 microns. Circle H&E for tech-only.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.