BCL6
Use
BCL6 antibody stains germinal center cells in lymphoid follicles, follicular cells and interfollicular cells in follicular lymphoma, a subset of diffuse large B-cell lymphomas, and Burkitt lymphoma, as well as the majority of Reed–Sternberg cells in nodular lymphocyte predominant Hodgkin lymphoma. It rarely stains mantle cell lymphoma and MALT lymphoma. Expression is seen in approximately half of CD30-positive anaplastic large cell lymphomas but is absent in other peripheral T‑cell lymphomas.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
BCL6
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded (FFPE) tissue block preferred; or one unbaked, unstained H&E slide (required) and two to three positively charged unstained slides (cut at 4‑5 microns) for each test/antibody ordered. Block and slide identifiers must match specimen ID on requisition.
Storage Instructions
Use cold pack for transport, not in direct contact with specimen. NYS clients must provide date and time of collection.