BRAF V600E
Use
A monoclonal antibody (IHC600) against mutant BRAF (V600E) permits fast assessment of the mutant protein expression throughout a tumor sample in hairy cell leukemia, some melanomas, and some thyroid carcinomas. BRAF mutation is a strong molecular marker of poor prognosis in colorectal carcinoma and can be used as evidence of a sporadic mechanism of mismatch repair deficiency.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
BRAF
Protein
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
FFPE tissue block preferred; or one unbaked unstained H&E slide (required) plus two to three positively charged unstained slides, 4‑5 microns, identifiers must match requisition.
Storage Instructions
Use cold pack for transport, but not in direct contact; NYS clients provide date/time of collection.