CD5
Use
CD5 is a transmembrane protein expressed on most thymocytes and immature peripheral T‑cells. It also stains normal B‑cells in the mantle zones of spleen and lymph nodes, as well as B‑cells in peritoneal and pleural cavities, and in fetal spleen and cord blood. It is positive in B‑cell chronic lymphocytic leukemia/small lymphocytic leukemia (CLL/SLL), mantle cell lymphoma (MCL), hairy cell leukemia (HCL), most T‑cell malignancies, and most thymic carcinomas, while usually negative in spindle cell thymoma.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
CD5
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred, or one unbaked, unstained H&E slide (required) plus two to three positively charged unstained slides (cut at 4‑5 microns); block and slide identifiers must match the requisition.
Storage Instructions
Use cold pack for transport; cold pack should not be in direct contact with specimen.