EGFR Amplification
Also known as: Epidermal growth factor receptor
Use
Fluorescence in Situ Hybridization (FISH) assay to detect amplification of the EGFR gene (7p11.2) using probes for EGFR and centromere 7. Applicable to various cancers including brain, lung, colorectal, gastric, and breast tumors.
Special Instructions
Available as 'Global' or 'Tech Only' service levels. For tech‑only submissions, the circled H&E slide is required. Transport with cold pack not in direct contact with specimen; New York State clients must provide date and time of collection.
Limitations
Not provided.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Send paraffin block. Also send circled H&E slide for tech‑only (required). Cut slides: H&E slide (required) plus 4 unstained slides cut at 4‑5 microns. Circle H&E slide for tech‑only.