GATA3
Use
GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. It is involved in luminal cell differentiation in the mammary gland and regulates genes involved in breast cancer differentiation and proliferation. Its expression correlates with estrogen receptor‑alpha (ER) status in breast cancer and is a novel marker for bladder cancer—it stains nearly all urothelial carcinomas but not prostate or renal carcinomas.
Special Instructions
Tech Only service. Storage and transport should use a cold pack that does not directly contact the specimen. For New York State clients, include collection date and time.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Not provided.
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred specimen. Alternatively, one unbaked, unstained H&E slide (required) plus two to three positively charged unstained slides (4‑5 microns each). Block and slide identifiers must match requisition.