HER2 Breast Cancer
Also known as: HER2 neu
Use
This test uses fluorescence in situ hybridization (FISH) to detect amplification of ERBB2 (HER2) relative to chromosome 17 centromere (CEN17) in breast cancer tissue, aiding in determining eligibility for HER2-targeted therapies and informing prognostic assessments.
Special Instructions
For global cases, a copy of the pathology report is required. Tech-only processing requires sending a circled H&E slide and 4 unstained slides at 4–5 µm. For New York State clients, please provide date and time of specimen collection. HER2 IHC report copy is required for global FISH cases.
Limitations
Not provided.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Send paraffin block. Also send circled H&E slide (required for tech-only) and 4 unstained slides cut at 4–5 microns.