Casandra
Casandra Test Code NG79473Version 1 (DRAFT)
Performing Lab
MYC (8q24)
Also known as: c-MYC
Clinical Use
Order TestUse
This FISH test employs MYC (8q24) probes to detect gene rearrangements associated with Burkitt lymphoma, other lymphomas, non-Hodgkin lymphoma (NHL), and B‑cell acute lymphoblastic leukemia (B‑ALL). MYC oncogene amplification is commonly associated with B‑cell malignancies, with >90% of Burkitt lymphomas and other aggressive lymphomas demonstrating 8q24/MYC amplification. This marker is available either separately or as part of the NHL FISH Panel.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
MYC
GeneAmplification(s)
Copy Number Alteration • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Bone Marrow
Volume
1-2 mL
Minimum Volume
Not provided
Container
sodium heparin tube (EDTA tube acceptable)
Storage Instructions
Refrigerate before shipping; cold pack not in direct contact