Casandra
Casandra Test Code NG32080Version 1 (DRAFT)
Performing Lab
NOTCH1 Mutation Analysis
Also known as: NOTCH1 Gene Sequencing
Clinical Use
Order TestUse
NOTCH1 mutations are common in T‑ALL, CLL, and mantle cell lymphoma. Mutations in ALL are associated with good prognosis, while mutations in CLL and mantle cell lymphoma are associated with poor prognosis.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Sanger
Biomarkers
NOTCH1
GeneSNV/Indel
Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
10 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Bone Marrow
Volume
2 mL
Minimum Volume
Not provided
Container
EDTA tube
Storage Instructions
Refrigerate before shipping; use cold pack (not in direct contact); ship same day; do not freeze.