Plasma Cell Myeloma FISH Panel
Also known as: Multiple Myeloma-MGUS, MM-MGUS FISH Panel
Use
The panel is used for the detection of FISH and chromosome aberrations useful in prognosis in plasma cell myeloma. As malignant plasma cells often have a low proliferation index, conventional cytogenetics frequently yields normal results. When this happens, interphase FISH studies can increase the abnormality detection rate.
Special Instructions
Specimens should be received in our laboratory within 72 hours of collection. Plasma cell enrichment was not validated using peripheral blood; therefore, it is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.
Limitations
Plasma cell enrichment will be performed on bone marrow samples unless otherwise directed by the client. It is not recommended to use peripheral blood as a screening specimen unless increased plasma cells are seen on blood smear.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
1-2 mL
Minimum Volume
Not provided
Container
sodium heparin tube or EDTA tube
Storage Instructions
Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.