Ploidy FISH for Molar Pregnancy
Also known as: CEN1/CEN11
Use
Ploidy FISH analyzes centromeres 1 and 11 to assess triploidy (associated with partial mole) vs. diploidy (associated with complete mole). It is used to differentiate complete molar pregnancy, partial mole, and abortus with hydropic changes by analyzing chromosomal composition.
Special Instructions
This test is available on a consult basis only. Use cold pack for transport, ensuring it is not in direct contact with the specimen. NYS clients please provide date and time of collection.
Limitations
This FISH test is limited to the analysis of centromeres 1 and 11 and does not evaluate other chromosomes or genetic abnormalities. It requires the specimen to contain villi and/or fetal tissue for accurate analysis.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
H&E slide (required) plus paraffin block.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
Causes for Rejection
Specimen must contain villi and/or fetal tissue.