RB (Retinoblastoma Protein)
Use
Retinoblastoma (RB) protein is a tumor suppressor that negatively regulates the cell cycle by interacting with transcription factors such as E2F1, PU1, ATF2, UBF, Elf1, and cAbl. Loss of RB function can result in uncontrolled cell growth, and aberrations in the RB gene are implicated in cancers including breast, colon, prostate, kidney, nasopharynx, and leukemia.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
RB
Protein
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered.