Use

SOX10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is also a useful marker in detecting both the in situ and invasive components of desmoplastic melanoma. SOX10 is diffusely expressed in schwannoma, neurofibroma, and granular cell tumor. SOX10 was not identified in any other mesenchymal and epithelial tumors except for myoepitheliomas and diffuse astrocytomas.