T-Cell Receptor Gamma Gene Rearrangement

Casandra

Casandra Test Code NG83580Version 1 (DRAFT)

Performing Lab

Lab NeoGenomicsLab Test ID N/ACPT Code 81342

T-Cell Receptor Gamma Gene Rearrangement

Also known as: T-Cell Gamma Gene Rearrangement, TCRG

Clinical Use

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Use

T-cell receptor (TCR) gene rearrangement analysis is commonly used for determining clonality in the diagnostic evaluation of T-cell lymphomas and leukemias. TCR beta gene (tested separately) and gamma gene rearrangement analysis (as provided in this test) together will detect most clonal TCR rearrangements in patients with T-cell lymphomas/leukemias. Results should be interpreted in clinical context for diagnosis of T-cell lymphoproliferative disorders.

Special Instructions

This test may be ordered concurrently with the T-Cell Receptor Beta Gene Rearrangement assay. Note: Test is DNA‑based. Please select Extract & Hold ‑ DNA if specimen hold service is desired. Note on FFPE: Paraffin block is preferred. Do not use zinc fixatives. If submitting slides, please use positively‑charged slides and 10% NBF fixative. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition. Note on Fresh Tissue: Not suitable for freeze & hold option.