Antimicrobial Combination Synergy, 2 Drugs
Use
This test determines the synergistic effect between two antimicrobial agents against a given bacterial isolate, helping clinicians identify combinations that exhibit enhanced inhibitory activity beyond that of individual drugs. Useful for guiding therapy in cases of resistant or difficult-to-treat bacterial infections.
Special Instructions
Requires pure culture of previously identified bacteria. Submission must indicate organism ID and the two drugs to be tested; missing information may delay processing. The isolate may be submitted on an agar slant, plate, or bacterial transport swab.
Limitations
Not FDA cleared or approved; developed and validated by Quest Diagnostics under CLIA. Viability of the culture is critical; frozen specimens are unacceptable. Test results depend on isolate quality and precise drug identification; transport conditions and frozen specimens may compromise viability.
Methodology
Other
Biomarkers
Result Turnaround Time
2-6 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Not provided
Minimum Volume
Not provided
Container
Agar slant or plate or bacterial transport swab
Collection Instructions
Pure culture of previously identified bacteria submitted on agar slant, plate, or bacterial transport swab. Swab of the isolate is also acceptable.
Causes for Rejection
Received frozen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Determined by viability |
| Refrigerated | Determined by viability |