CBFB-MYH11 inv(16), Quantitative, Real-Time PCR
Use
This Real‑Time Quantitative (Reverse Transcription Polymerase Chain Reaction) assay amplifies the CBFB/MYH11 fusion transcript to detect the chromosome inversion inv(16) or translocation t(16;16) commonly associated with Acute Myeloid Leukemia (AML). It can be utilized for minimal residual disease (MRD) monitoring and to assess relapse risk in patients with inv(16)/t(16;16) AML.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
PCR-based (RT-PCR)
Biomarkers
CBFB, MYH11
Gene
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL preferred, minimum 2 mL
Minimum Volume
2 mL
Container
EDTA (lavender‑top) tube
Collection Instructions
Collect 5 mL of whole blood in an EDTA (lavender‑top) tube. Also acceptable: EDTA (royal blue‑top), lithium heparin or sodium heparin (green‑top) tube
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