Chloride, 24‑Hour Urine with Creatinine

Use

Urine chloride excretion approximates dietary chloride intake—which typically parallels sodium intake—and can help evaluate electrolyte and acid–base balance. Elevated levels may be seen in dehydration, diabetic acidosis, Addison’s disease, or salt‑losing renal disease, while decreased levels may indicate congestive heart failure, severe diaphoresis, or hypochloremic metabolic alkalosis due to prolonged vomiting.