Use

This test is used to detect the SRY chromosome region (Yp11.3) and the X chromosome centromeric region using fluorescence in situ hybridization. It may be useful in cases of discrepancy between chromosomal sex and phenotypic sex, studies of marker chromosomes of suspected sex chromosome origin, and Y chromosome morphology studies. It can detect deletions or duplications involving the SRY gene and assess sex chromosome abnormalities such as sex reversal, Turner syndrome, or disorders of sex development.