Use

This fluorescence in situ hybridization (FISH) assay detects a partial deletion of the Wolf‑Hirschhorn syndrome (WHS) critical region in chromosome 4p16.3, aiding in the diagnosis of WHS, a rare chromosomal deletion disorder characterized by growth deficiency, distinctive craniofacial features (‘Greek warrior helmet’), seizures, hypotonia, microcephaly, and other congenital malformations. The clinical severity often correlates with deletion size. ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/nmmcpathology/test/571983?utm_source=openai))