HLA‑B27 Antigen
Also known as: Ankylosing Spondylitis, Flow
Use
The HLA‑B27 antigen is associated with ankylosing spondylitis (found in approximately 90% of patients) and reactive arthritis/Reiter’s disease (approximately 80% of patients). Its presence indicates genetic predisposition to these spondyloarthropathies, aiding in their diagnosis and evaluation.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
Sodium heparin (green‑top) tube
Collection Instructions
Whole blood collected in a sodium heparin (green‑top) tube. EDTA (lavender‑top) or ACD‑A or ACD‑B (yellow‑top) tubes also acceptable for NY variant; for standard test, only sodium heparin.
Storage Instructions
Transport at ambient temperature
Causes for Rejection
Lithium heparin tube, hemolysis, clotted specimen, received frozen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days ambient |
| Refrigerated | 5 days refrigerated |
| Frozen | Unacceptable |