Casandra
Casandra Test Code QD21097Version 1 (DRAFT)
Performing Lab
HLA‑DRB1, DQB1 Low Resolution
Clinical Use
Order TestUse
This test performs low‑resolution typing of human leukocyte antigen (HLA) class II loci DRB1 and DQB1. It is used to determine antigen-level HLA types for purposes such as transplant compatibility assessment or donor matching at a basic resolution.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
PCR-based (PCR)
Biomarkers
DRB1, DQB1
GeneSNV/Indel
Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
5‑14 mL
Minimum Volume
5 mL
Container
Lavender (EDTA) tube (also acceptable: ACD yellow‑top; green‑top heparin tube)
Collection Instructions
Whole blood collected in an ACD (yellow‑top), sodium or lithium heparin (green‑top), or EDTA lavender‑top tube; 4 buccal swabs acceptable
Storage Instructions
Ambient‑only transport
Causes for Rejection
Frozen specimens; citrated tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 Days (30 Days for Buccal swabs) |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |
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