Levetiracetam, Immunoassay
Also known as: Keppra
Use
LEV is currently used as an anti‑epileptic drug for the treatment of adult partial seizures particularly as an add‑on therapy for refractory patients. It also has potential for other anxiety and cognitive disturbances. Levetiracetam testing helps optimize dosage, verify adherence, detect toxicity, and monitor the impact of recent health changes affecting drug clearance or kidney function. Results are collected at trough, 0.5 to 1 hour before the next oral dose, once steady state is reached approximately 2 weeks after treatment onset. Therapeutic trough range is generally 12 to 46 µg/mL, with levels above 46 µg/mL potentially toxic.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (Immunoassay)
Biomarkers
Levetiracetam
Analyte
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
0.5 mL
Container
Red‑top tube (no‑gel)
Collection Instructions
Collect 1 mL serum in red‑top tube (no‑gel). Trough at steady‑state; 0.5 to 1 hour pre‑dose.
Causes for Rejection
Specimens collected in gel barrier tubes (SST • PST) or unspun red‑top tube (no‑gel)
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 21 days |
| Frozen | 30 days |
Other tests from different labs that may be relevant