Myelin Basic Protein
Also known as: MBP
Use
The concentration of MBP is often increased in patients with demyelinating diseases such as multiple sclerosis and may be increased in patients with head injury, central nervous system trauma, tumor, stroke, and viral encephalitis.
Special Instructions
CSF must be clear. Do not centrifuge. CSF collection tube #4 is preferred; submitting 4th lumbar puncture collection tube minimizes blood contamination.
Limitations
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Methodology
Immunoassay (RIA)
Biomarkers
LOINC Codes
- 2638-5
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1.2 mL (0.5 mL minimum)
Minimum Volume
0.5 mL
Collection Instructions
Transport 1.2 mL CSF (Min: 0.5 mL). CSF must be clear. Do not centrifuge. CSF collection tube #4 preferred; submitting 4th lumbar puncture collection tube minimizes blood contamination.
Causes for Rejection
Hemolysis, Xanthochromia/RBCs in CSF
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 21 days |