Casandra
Casandra Test Code QD99464Version 1 (DRAFT)
Performing Lab
Topiramate
Clinical Use
Order TestUse
Topiramate therapeutic drug monitoring assesses blood concentrations of the anticonvulsant topiramate, which is used in the management of seizure disorders, epilepsy, and migraine prevention. Measuring serum or plasma levels aids evaluation of therapeutic response, adjustment of dosing for efficacy, and avoidance of toxicity.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Mass Spectrometry
Biomarkers
Topiramate
AnalyteTopiramate concentration
Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
red‑top tube (no gel)
Patient Preparation
Draw at peak (2‑4 hours after dose) or trough (0.5‑1 hour before dose) at steady state
Causes for Rejection
Gel barrier/serum separator tube (SST)
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 30 days |
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