Varicella‑Zoster Virus Antibody (IgG)
Also known as: Varicella IgG Antibodies, VZV IgG, Shingles, Herpes Zoster IgG Ab, Chicken Pox
Use
This test detects IgG-class antibodies to varicella‑zoster virus (VZV) and is useful for determining an individual’s immune status or aiding in the diagnosis of VZV infection. A positive IgG indicates the presence of antibodies; while it cannot distinguish between past and current infection, when active disease is not suspected, a positive result most likely indicates immunity from prior infection. However, vaccinated individuals may have lower antibody levels that might evade detection by this assay. (Quest Diagnostics FAQ)([questdiagnostics.com](https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq117v1?utm_source=openai))
Special Instructions
Not provided.
Limitations
A positive IgG result cannot differentiate between active and past infection; interpretation requires clinical correlation including patient history and presentation. Additionally, antibody levels from vaccination may be lower than those from natural infection, possibly leading to false-negative results in vaccinated individuals. (Quest Diagnostics FAQ)([questdiagnostics.com](https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq117v1?utm_source=openai))
Methodology
Immunoassay
Biomarkers
Varicella zoster virus Ab.IgG
Protein
LOINC Codes
- 5403-1 - VZV IgG Ser IA-aCnc
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Container
Red/Yellow top tube
Storage Instructions
Refrigerate 2°‑8° C
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
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