VMA (Vanillylmandelic Acid), 24‑Hour Urine without Creatinine

Casandra

Casandra Test Code QD81118Version 1 (DRAFT)

Performing Lab

Lab Quest DiagnosticsLab Test ID 934

VMA (Vanillylmandelic Acid), 24‑Hour Urine without Creatinine

Also known as: VMA, VMA, 24hr Urine

Clinical Use

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Use

Measurement of vanillylmandelic acid (VMA) in a 24‑hour urine collection is used for detection and monitoring of catecholamine‑secreting tumors such as neuroblastoma and occasionally pheochromocytoma. Elevated levels may suggest such tumors, though additional confirmatory testing is required.

Special Instructions

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Limitations

Elevated VMA alone is not diagnostic; up to 20‑32% of neuroblastoma patients may not have elevated VMA. VMA is not the preferred analyte for pheochromocytoma (metanephrines are more sensitive).

Test Details

Methodology

Mass Spectrometry

Biomarkers

Vanillylmandelic Acid (VMA)

Analyte

VMA, 24 hr Urine • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Result Turnaround Time

1-5 days

Specimen

Urine

Volume

Not provided

Minimum Volume

Not provided

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