VMA (Vanillylmandelic Acid), 24‑Hour Urine without Creatinine

Also known as: VMA, VMA, 24hr Urine

Clinical Use

Use

Measurement of vanillylmandelic acid (VMA) in a 24‑hour urine collection is used for detection and monitoring of catecholamine‑secreting tumors such as neuroblastoma and occasionally pheochromocytoma. Elevated levels may suggest such tumors, though additional confirmatory testing is required.

Special Instructions

Not provided.

Limitations

Elevated VMA alone is not diagnostic; up to 20‑32% of neuroblastoma patients may not have elevated VMA. VMA is not the preferred analyte for pheochromocytoma (metanephrines are more sensitive).

Test Details