11-Deoxycortisol
Also known as: 11-Desoxycortisol, Compound S for Metyrapone Test
Use
Evaluate hypothalamic-pituitary-adrenal axis and pituitary ACTH reserve
Special Instructions
To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Limitations
A reduced response to the metyrapone test occurs in patients with hypoadrenalism or hypopituitarism and in some patients with diseases of the hypothalamus. Patients with myxedema, some pregnant patients, and those on oral contraceptives may respond poorly. Recently administered isotopes may cause test interference, leading to rejection of the sample.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 1657-6
- 1657-6
Result Turnaround Time
6-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Transfer the serum into a LabCorp PP transpak frozen purple tube with screw cap (LabCorp N° 49482). Freeze immediately and maintain frozen until tested.
Patient Preparation
No isotopes administered 24 hours prior to venipuncture
Storage Instructions
Freeze.
Causes for Rejection
Recently administered isotopes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 day |
| Refrigerated | 1 day |
| Frozen | 2 years |
Other tests from different labs that may be relevant