Use

Used to assess adrenal gland function by measuring 11‑deoxycortisol levels at two time points (baseline and post‑metyrapone), e.g., as part of metyrapone testing or ACTH stimulation, to evaluate cortisol biosynthesis and hypothalamic‑pituitary‑adrenal axis reserve. 11‑deoxycortisol is the immediate precursor of cortisol and increases after metyrapone administration, aiding in diagnosis of congenital adrenal hyperplasia and enzyme deficiencies.