17-Hydroxypregnenolone 60-Minute Timed Specimen

Casandra

Casandra Test Code AR08890Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0092337CPT Code 84143

17-Hydroxypregnenolone 60-Minute Timed Specimen

Also known as: OHPRGN 60

Clinical Use

Order Test

Use

The 17-Hydroxypregnenolone 60-Minute Timed Specimen test measures the level of 17-Hydroxypregnenolone in the serum or plasma after a specific duration, aiding in the evaluation of adrenal function and the diagnosis of conditions related to steroid synthesis abnormalities. This test is crucial for assessing disorders like congenital adrenal hyperplasia and for monitoring the effectiveness of treatment in these conditions.

Special Instructions

For accurate results, it is essential to maintain the specimen frozen during storage and transport. Ensure that serum or plasma is separated from cells as soon as possible or within two hours of collection to avoid degradation.

Limitations

The test may be affected by improper handling and storage, such as failing to freeze the specimen immediately, which can lead to degradation of the analyte. Another limitation includes potential interference from other steroids or similar compounds in the blood, affecting the specificity of the test results. Additionally, results must be interpreted in the context of the patient's clinical presentation and other diagnostic findings.

Test Details

New York Approved

Methodology

Mass Spectrometry

Biomarkers

17-Hydroxypregnenolone

Analyte

Concentration • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

49325-4

Result Turnaround Time

1-5 days

Specimen

Serum

Volume

0.5 mL

Minimum Volume

0.25 mL

Container

ARUP Standard Transport Tube

Collection Instructions

Collect specimen in a serum separator tube. Alternative acceptable tubes include plain red, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin). Separate serum or plasma from cells ASAP or within 2 hours of collection.