β2-Glycoprotein 1 Antibodies, IgA, IgG, IgM
Also known as: Anti-β2 Glycoprotein 1, Beta-2 Glycoprotein 1 Antibodies, IgG, IgA, IgM
Use
Assess the risk of thrombosis in patients who may be at risk for antiphospholipid syndrome (APS). This test should be used in conjunction with current traditional anticardiolipin and anticoagulant tests.1
Special Instructions
The test findings should not be used in isolation to diagnose antiphospholipid syndrome; it should always be used in conjunction with other diagnostic criteria and traditional testing methods such as anticardiolipin and anticoagulant tests.
Limitations
Anti-β2-glycoprotein 1 antibodies should not be employed alone as a screening tool for APS. Approximately 30% of patients might show discordant results between anticardiolipin antibodies and β2-Glycoprotein 1 antibodies. About 20% of patients who test negative for anticardiolipin antibodies will test positive for β2-GP1. Moreover, anti-β2-GP1 response might not support an APS diagnosis if it concomitantly shows negative lupus anticoagulant and anticardiolipin outcomes.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 56152-2
- 16135-6
- 21108-6
- 16136-4
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 7 days |
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