Acute Myelocytic Leukemia (AML) Profile, FISH
Use
Diagnostic and prognostic test for acute myeloid leukemia; detection rate is 80% of the known chromosome causes of AML.
Special Instructions
Indicate pertinent clinical diagnosis and previous cytogenetic studies on the test request form. Proper specimen handling and transportation are critical, and sterile techniques should be utilized where possible.
Limitations
The test is restricted to detecting molecular mutations or chromosomal alterations targeted by the included probes. Alterations not targeted will not be detected, and the test results should be considered as part of a comprehensive cytogenetic analysis and hematologic evaluation.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 31208-2
- 62361-1
- 62360-3
- 48674-6
- 50398-7
- 48672-0
- 11502-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal
Collection Instructions
Utilize sterile technique and Labcorp transport kits when possible.
Storage Instructions
Transport to the testing laboratory at room temperature; use of a cool pack or a Labcorp transport kit is acceptable. Do not allow samples to overheat or freeze.
Causes for Rejection
Broken Vacutainer®; broken or stained slides; decalcified bone core; frozen specimen; quantity not sufficient for analysis
Other tests from different labs that may be relevant