Allergen, Occupational, Isocyanate TDI
Also known as: ISO TDI
Use
The Allergen, Occupational, Isocyanate TDI test is used to measure the presence of allergen-specific IgE antibodies related to isocyanate, specifically Toluene Diisocyanate (TDI). These antibodies are indicative of occupational exposure to TDI, which is commonly used in the production of polyurethane products. The test results help in diagnosing potential allergic reactions to TDI, which can cause respiratory issues such as asthma. A quantitative measurement of IgE antibodies is carried out to assess the risk and exposure level.
Special Instructions
Multiple patient encounters should be avoided during the testing process.
Limitations
The increase in allergen-specific IgE concentrations may not correspond with the degree of clinical response or skin testing results when challenged with a specific allergen. Results showing allergen-specific IgE between 0.10-0.34 kU/L have undetermined clinical relevance and should be interpreted by specialists. Moreover, a negative result does not necessarily rule out clinical allergy or anaphylaxis. It is vital to correlate laboratory results with patient's clinical history and in vivo reactivity to specific allergens.
New York Approved
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
LOINC Codes
- 7431-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.25 mL
Collection Instructions
Collect serum in serum separator tube. Separate serum from cells ASAP or within 2 hours of collection. Transfer serum to an ARUP Standard Transport Tube.
Causes for Rejection
Hemolyzed, icteric, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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