Anti-Sa Ab, IgG (RDL)
Also known as: ACV, Anti-Citrullinated Vimentin, SA, Vimentin
Use
Anti-Citrullinated Vimentin (Sa) antibodies are highly specific for rheumatoid arthritis (RA). They are found in early polyarthritis, can identify patients that are anti-CCP and IgM-RF antibody-negative, and predict a more aggressive RA disease course. Disappearance of anti-Sa IgG antibodies 3 months after initiation of treatment is associated with less radiographic progression.
Special Instructions
This test is a component of RAdx5, SeroNegRAdx3. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 54022-9
- 54022-9
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |
Other tests from different labs that may be relevant