Bordetella pertussis Antibody, IgM by ELISA with Reflex to Immunoblot

Casandra

Casandra Test Code AR26921Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2001769CPT Code 86615

Bordetella pertussis Antibody, IgM by ELISA with Reflex to Immunoblot

Also known as: BORDM

Clinical Use

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Use

The Bordetella pertussis Antibody, IgM by ELISA test is used to detect IgM antibodies against Bordetella pertussis. It is not the primary diagnostic tool, as it has limited clinical utility due to potential false positives. The CDC recommends using PCR for Bordetella pertussis and/or culture as primary tests. The ELISA test serves as a part of a reflex testing strategy towards immunoblot for further confirmation, which helps in determining recent exposure or immunization status.

Special Instructions

This test should be performed when CDC-recommended tests are not applicable or as part of a reflex testing protocol. Samples should be clearly marked as 'acute' or 'convalescent' if applicable, and parallel testing with convalescent specimens within 30 days of the acute specimen is preferred.

Limitations

The ELISA test for Bordetella pertussis IgM may yield false-positive results. Treatment decisions should be based on Bordetella pertussis IgM immunoblot results. The test has not been cleared or approved by the FDA; it is developed and performed in a CLIA-certified laboratory, for clinical purposes. This test is not approved in New York State, and specimens collected there require specific permission for processing.

Test Details