BRAF V600E Mutation IHC without interpretation
Also known as: Immuno Histo Chemistry, Histopathology, BRAF Mutation, Melanoma
Use
This test detects the presence of BRAF V600E–mutant protein in formalin‑fixed, paraffin‑embedded (FFPE) tissue specimens using immunohistochemistry (IHC). It serves as a rapid screening tool to identify tumors harboring this specific mutation, which is commonly observed in melanoma and other malignancies and may inform eligibility for targeted therapies.
Special Instructions
This is a technical component only and does not include pathologist interpretation. For diagnostic evaluation, a separate pathology consultation or interpretation test (e.g., IHC interpretation or pathology consultation) must be ordered.
Limitations
This assay only assesses protein expression and does not provide molecular-level mutation information; only the presence of mutant BRAF V600E protein is detected. Interpretation should be conducted in the full clinical and diagnostic context, including other histopathologic findings and clinical history.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Storage Instructions
Store specimen at room temperature.
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