C-1-Esterase Inhibitor Panel
Also known as: C1 INH PAN
Use
The C-1-Esterase Inhibitor Panel is used for the diagnosis and monitoring of hereditary angioedema (HAE) and other conditions associated with C1-INH deficiency. It assesses C1 esterase inhibitor levels and functionality, as well as complement component 4 levels, which can be indicative of HAE or other related immune disorders. The test helps differentiate between hereditary and acquired forms of angioedema.
Special Instructions
Not provided.
Limitations
Abnormal concentrations of functional C1-INH may require confirmation using a new sample to rule out the effects of specimen inactivation due to improper collection, transport, or handling conditions. The test results should be considered alongside clinical findings as certain conditions may affect complement levels variably.
New York Approved
Methodology
Immunoassay (Immunoturbidimetry)
Biomarkers
LOINC Codes
- 4477-6
- 4498-2
- 48494-9
- 4477-6
- 48494-9
- 4498-2
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
1.0 mL/tube
Container
ARUP Standard Transport Tubes
Collection Instructions
Serum separator tube. Separate serum from cells ASAP or within 2 hours of collection, transfer into ARUP Standard Transport Tubes and freeze immediately.
Storage Instructions
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Causes for Rejection
Non-frozen specimens.
Other tests from different labs that may be relevant