Use

Fibrinogen is a plasma glycoprotein that can be transformed into a fibrin clot in response to vascular or tissue injury. The combination of elevated fibrinogen with other cardiovascular disease (CVD) risk factors produces an additive risk and may substantially increase disease potential. Low levels of fibrinogen are associated with bleeding, most commonly due to liver disease or disseminated intravascular coagulation (DIC). As an acute-phase reactant, elevated levels may indicate inflammation or increased atherosclerotic risk.